Genetic Determinants of P2Y12 Inhibitors and Clinical Implications
نویسندگان
چکیده
منابع مشابه
Pharmacology and clinical trials of reversibly-binding P2Y12 inhibitors.
The important role of the P2Y12 receptor in amplification of platelet activation and associated responses and the limitations associated with clopidogrel therapy have led to the development of novel inhibitors of this receptor. Three reversibly-binding P2Y12 inhibitors are in phase 3 development, ticagrelor, cangrelor and elinogrel. The pharmacology and clinical trial data for each of these inh...
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ژورنال
عنوان ژورنال: Interventional Cardiology Clinics
سال: 2017
ISSN: 2211-7458
DOI: 10.1016/j.iccl.2016.08.010